In a Q&A format use colons, not quotation marks. A quotation within a quotation takes single marks: “Lady Gaga performed her rendition of ‘Imagine’ at the Human Rights Campaign’s 13th Annual National Dinner in Washington, D.C.”

Quotation marks are sometimes used to indicate that a term is used in a nonstandard (or slang), ironic, or other special sense. Nicknamed scare quotes, they imply “This is not my term” or “This is not how the term is usually applied.” Scare quotes should be used carefully because they can convey condescension and irritate readers. Preferred use is only to indicate that a word or phrase is used in an ironic or opposite sense: “Child protection” sometimes fails to protect.

In works of philosophy, single quotation marks are used by some authors for similar purposes. However, following Chicago Manual style, use regular quotation marks and apply the guidelines above.

Also see Internal and Terminal Punctuation and Names: Titles of Works.